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Transforming healthcare through advanced R&D

Cross the Next Frontier in Brain Medicine

Cross the Next Frontier in Brain MedicineCross the Next Frontier in Brain MedicineCross the Next Frontier in Brain Medicine

Transforming healthcare through advanced R&D

Cross the Next Frontier in Brain Medicine

Cross the Next Frontier in Brain MedicineCross the Next Frontier in Brain MedicineCross the Next Frontier in Brain Medicine

Our Mission

  

Central nervous system (CNS) disorders represent one of the largest and most enduring areas of unmet medical need worldwide. Neurodegenerative, neuroinflammatory and genetic neurological diseases continue to impose profound clinical, societal, and economic burdens. Despite meaningful scientific progress over the past decades, therapeutic innovation in CNS has lagged other fields—due in large part to the biological complexity of the brain and the challenges of achieving adequate drug exposure in the central nervous system.


BraneX Bio was founded to address these fundamental limitations. We are an early-stage biotechnology company backed by leading investors and seasoned biotech executives, united by a singular mission: to enable safe, precise, reliable and therapeutically meaningful delivery of advanced medicines to the brain.


Our approach centers on building next-generation precision brain-exposure platforms designed to unlock the full potential of diverse therapeutic modalities, including biologics and other innovative formats. By integrating deep expertise in disease biology, translational science, molecular engineering and development strategy, we aim to systematically expand what is possible in CNS drug development.


Through a focused pipeline of first- and best-in-class programs, BraneX Bio is working to transform how brain diseases are treated—moving beyond incremental progress toward safe, durable, disease-modifying solutions for patients with urgent medical needs.


 Please click 'Positions Open' at the bottom of the page to explore current opportunities at BraneX Bio Shanghai. 

Leadership Team

Chief Scientific Officer (CSO): Gunasekaran (Guna) Kannan, PhD

  

Guna Kannan is the Founder and Chief Scientific Officer of BraneX Bio, bringing more than 25 years of experience in biologics drug discovery, antibody platform development, and translational research. He has led and contributed to multiple large molecule programs from early target validation through candidate selection, preclinical development, and IND-enabling strategy. Guna held senior scientific roles at Amgen and Denali Therapeutics, where he was responsible for therapeutics discovery, design and optimization, and translational development. His work spanned multiple therapeutic areas including neuroscience, oncology, metabolic disorders, and inflammation, with a focus on advancing biologics from concept to clinical readiness. Guna possesses deep end-to-end expertise across the R&D continuum and has extensive experience working in cross-functional environments and collaborating with internal and external stakeholders to advance high-impact therapeutic programs.

Chief Operating Officer (COO): Feng Pan, PhD

With over 20 years of experience in CNS disease biology research and drug discovery as well as R&D management, Feng possesses deep knowledge in the global biopharmaceutical R&D landscape and operational frameworks. He has held key R&D positions at multinational pharmaceutical companies including Eli Lilly and Company and Pfizer, as well as leading domestic pharmaceutical company (Simcere Pharmaceutical). He has a strong understanding of target biology in neurodegenerative and psychiatric disorders and has accumulated extensive experience in drug discovery and development. He has demonstrated exceptional capability in R&D team construction, portfolio project initiation and milestone achievements. Leveraging his deep insights into the CNS drug development ecosystem both globally and in China, he will support BraneX Bio in building an efficient R&D operating system and accelerating the advancement of innovative therapeutics from preclinical development to clinical implementation.

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